Reduction Mammaplasty and Intra-Operative Radiotherapy (IORT) in Conservative Surgery
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Accelerators Development for Intraoperative Radiation Therapy
The "Intra Operative Radiation Therapy" (IORT) consists in delivering a single high dose on a tumour bed soon after surgery resection. The "IORT Project", funded by the Italian Ministry of Research (MURST), was started in 1998 from ENEA (Italian National Agency for New Technologies, Energy and the Environment) and is aimed to design and construct two innovative IORT systems (named IORT-1 and IO...
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PURPOSE To assess efficacy and tolerance of intra-operative radiation therapy (IORT) in patients suffering from locally advanced rectal cancer, treated with preoperative radiotherapy followed by surgical resection. METHODS AND MATERIALS In this French, multicenter, comparative, phase III study, 142 patients with locally advanced rectal cancer (T3 or T4 or N+, and M0), treated with a 4-week pr...
متن کاملThe Italian “iort Project”
The “Intra Operative Radiation Therapy” (IORT) represents the latest technological frontier in radiotherapy. The technique utilizes accelerated electrons, as from a tailored designed EB-machine, to destroy rapidly spreading malignant cancer cells and it is appraised to allow a 15% general increase of cancer patients survival. The Italian “IORT Project”, funded by the Italian Ministry of Researc...
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Background: The aim of conservative surgery for treatment of breast cancer is obtaining satisfactory aesthetic results. Segment-based surgery, which must be followed by radiotherapy (RT), is considered the treatment of choice for most breast cancer patients. Single-dose intraoperative radiation in the tumor bed (IORT) is a promising radiation technique that is more rapid than conventional RT an...
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BACKGROUND AND PURPOSE The purpose of this study is to analyze the patterns of local recurrence (LR) after intra-operative radiotherapy (IORT) containing multimodality treatment of locally advanced rectal carcinoma (LARC). METHODS AND MATERIALS Two hundred and ninety patients with LARC who underwent multimodality treatment between 1994 and 2006 were studied. For patients who developed LR, the...
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